QR355 Virology

In order to successfully invade a new species, lentiviruses must overcome restriction factors, dominant blocks to replication, and be able to make use of available host factors such as entry receptors for replication. Human immunodeficiency virus (HIV-1) infection is blocked at …

Despite the importance of host species choice of mosquito vectors to the epidemiology and control of malaria, our understanding of the ecological and evolutionary factors that drive the host species preference in these vectors is very limited. My PhD thesis aimed to experimental…