Thesiss

TNF-α acutely increases leptin production in animals and humans. Insulin-mediated glucose uptake potently regulates leptin production in adipocytes. Yet, TNF-α inhibits insulin signaling and decreases Akt expression, which was demonstrated to regulate leptin production in adipoc…

Cryolipolysis is a noninvasive clinical procedure to locally reduce adipose tissue. During the procedure, paddles that are maintained at a prescribed temperature (commonly -14 ℃ and 3.1 ℃) are placed in good thermal contact with the skin. Cryolipolysis was inspired by panniculit…