Thesiss

B lineage cells regulate BAFF-R expression to utilize and manipulate the powerful BAFF/BAFF-R survival and proliferation axis. To elaborate B cells’ mechanisms of receptor regulation within the BAFF/BAFF-R axis, this work explored physiological regulation in normal B cells as we…

B cells are the central component of the humoral immune system and critical for long term immunity against all forms of pathogens. Antibodies represent one of the earliest lines of defense within the adaptive memory response and are the major effectors of vaccine mediated protec…