Puberty involves the complex integration of a variety of neural and endocrine factors. The efficacy of gonadal steroid hormones, testosterone (T) and 17β-estradiol (E2), to exert inhibitory effects gradually declines during puberty. The importance of diminished hormonal sensitiv…
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Depression and social anxiety increase in prevalence during adolescence and are linked to long-term difficulties. The aetiology of increased onset of depression and social anxiety during adolescence is likely to be complex, encompassing social, biological and neuropsychological …
Pubertal timing is a human life history variable representing a trade-off between early reproduction and continued growth. Dominance is an important feature to male mate value. These two variables should have far-reaching effects on adult male life. Chapter 1 reviews evolution, …
Mammalian oocytes begin their meiotic division during embryonic life and arrest around birth at a G2-like phase of the cell cycle. These oocytes then enter a growth phase, during which they are not competent to resume meiosis. Meiotic competence is acquired by oocytes that have …
Adolescent pregnancies are a concern worldwide. This study investigated how pregnancy and lactation during adolescence affects the growth and nutritional status of young mothers in rural developing country settings. A prospective cohort study was conducted among 12-19 year old p…
Maturation of social cognition and a gain in social proficiency are universal aspects of adolescent development that prepare an individual for adulthood. Social cognition involves the perception and interpretation of social cues, followed by the generation of a behavioral respon…
Exercise-induced anaphylaxis (EIA) is a rare severe disease in which patients express asthmatic and allergic symptoms. Little is known about EIA and its pathology. This manuscript presents an hypothesis that combined hormonal (estrogen and progesterone) contraceptive use and str…
Life history theory dictates that organisms should precisely allocate investment of their limited resources, including energy, to a variety of tasks to serve natural selection’s ultimate goal: reproduction. In adolescence, menarche occurs as growth velocity is tapering off, prov…
This study examines the relationship between puberty and mood in an epidemiological sample, describing trends in mood and quality of life (QoL) accompanying puberty, relationships between pubertal stage and mood diagnoses, and the effects of precocious puberty on mood. 1,163 car…