The understanding of the genetic architecture of a desirable trait is vital in enabling sustainable increased yields of a root crop such as cassava, especially in a low-input agricultural system. The understanding of desirable trait architecture is also vital for the sustained a…
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Regeneration, the replacement of lost or damaged body parts, and biomineralisation, the biologically controlled formation of minerals, are important and widespread abilities in the animal kingdom. Both phenomena have a complex evolutionary history; thus their study benefits from…
Introduction: Dupuytren's disease (DD) is an ill-defined fibroproliferative disorder affecting the palms of the hands of certain patient groups. Whether changes in DD fibroblasts are due to genetic alterations alone or related to metabolic dysregulation has not yet been investig…
The molecular processes that govern speciation are not completely understood, especially within marine ecosystems. Insight on the topic of speciation can be provided by focusing on adaptive radiations, because of the rapid amount of lineages that have arisen within a short natur…
Cancer progression is an evolutionary process: somatic mutations can confer selective advantages to certain cells, eventually causing them to abnormally proliferate. Parallels can be drawn between the evolution of organismal populations and cancer cell populations. In both, sele…
Biological responses to environmental perturbations can be transmitted across multiple generations through non-genetic mechanisms, and can potentially sensitize or harden offspring to those perturbations. Understanding these multigenerational effects in natural populations could…
The colonization of land by plants approximately 500 million years ago (Ma) is one of the most important events in the history of complex life. Land plants, hereafter referred to as “embryophytes,” comprise the ecological foundation of every major terrestrial biome, making them …
Alcohol use disorder and alcohol related phenotypes are genetically influenced, complex traits. Complex traits have proved challenging for connecting genotype to phenotype because they arise from a number of genetic factors capable of interacting with each other and the environm…