Legionella species are gram-negative bacteria that are known to cause a severe lung infection,
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Analysis was performed on data from cows born between 1984-1994 in five government dairy herds in Malaysia. Study objectives were to; (i) describe herd performance for reproductive and production indices, (ii) investigate associations between birthweight, age standardized weight…
Channel catfish (CCF), Ictalurus punctatus, gut cells associated with innate or acquired immunity were characterized based on their reaction to monoclonal antibodies (mAb) using flow cytometry, histochemistry, immunohistochemistry, and enzyme staining techniques. Isolation of gu…
Photobacterium damsela subsp. piscicida, formerly Pasteurella piscicida, is an important new pathogen of hybrid striped bass cultured in brackish water on Louisiana mariculture farms. Louisiana isolates compared with strains of P. damsela subsp. piscicida from Greece, Japan, Isr…
Equine Infectious Anemia Virus (EIAV) is a lentivirus closely related to Human Immunodeficiency Virus (HIV). Thrombocytopenia is a consistent and early hematological abnormality in horses acutely infected with EIAV. As with HIV, multifactorial mechanisms, including immune-mediat…
Pasteurellosis has plagued rabbits since time immemorial. The treatment of Pasteurella multocida infection is often frustrating. The goal was to investigate application of a broad spectrum vaccine based on conserved gram-negative bacterial core antigens (GNCA) that would provide…
Since 1980, there have been at least 34 confirmed deaths or serious hemorrhagic illnesses in captive Asian and African elephants located in North America, Europe and the Middle East associated with newly recognized endotheliotropic herpesviruses. They are known as the elephant e…
Subcellular fractionation using sucrose gradient centrifugation was established for isolating dense granules and other organelles of Eimeria tenella sporozoites. Identity of the organelles was confirmed using transmission electron microscopy. Spherical dense granules measured 18…
Two H13 avian influenza viruses (AIVs) were characterized using the intracranial pathogenicity index technique and by measuring viral replication after oculonasal inoculation of chicks, poults, and ducklings. The H13N2 isolates were non-pathogenic in chickens, replicated in turk…
The purpose of this work was to investigate the interaction of the pro-inflammatory cytokine, IFN-γ, and the anti-inflammatory cytokines, TGF-β and IL-10, in the subclinical and clinical stages of Johne's disease. A retrospective quantitative analysis of IFN-γ, IL-10 and TGF-β m…
Human hepatitis E virus (HEV) was first reported in 1980 and is now considered a major cause of acute non-A, non-B hepatitis in humans. HEV infection is reported throughout the world and occurs in epidemic form in developing countries where the disease is endemic and is often as…
Channel catfish leukocytes demonstrated cytoplasmic staining patterns very similar to mammalian leukocytes when stained for acid phosphatase, a-napthyl butyrate esterase, b-glucuronidase and Sudan Black B. Monocytes, macrophages, neutrophils and possibly immature lymphocytes wer…
This is the first characterization of paddlefish (Polyodon spathula ) leukocytes and lymphoid tissues by enzyme cytochemistry, and the first study of lymphoid tissue ontogeny. Paddlefish monocytes/macrophages, T and B lymphocytes and granulocytes were positive for acid phosphata…
This dissertation focuses on the life cycles and systematics of 3 molecular strains of Mesocestoides tapeworms that represent different evolutionary lineages (clades A, B, and C) found in Californian domestic carnivores and wildlife. In Chapter 1, life cycles of Mesocestoides cl…
This study characterized the oxidative biotransformation capacity of the hepatic cytochrome P-450 system of selected avian species representing the Galliformes (chicken, turkey and Japanese quail) and Anseriformes (goose, Pekin duck, Khaki Campbell duck, and Muscovy duck) orders…
This thesis research has been presented in several individual studies on Avian Pnemovirus (APV) infection in turkeys. An RT-PCR assay was developed for the specific detection of APV infection in turkeys. Primers derived from the Matrix gene of APV were found to be specific and s…
The contribution of circulating maternally derived antirotavirus IgG (rIgG) on protection of the intestinal mucosal surfaces against challenge with avian rotavirus was investigated. Turkey poults from specific-pathogen-free (SPF) hens hyperimmunized with group A avian rotavirus …
Senecavirus A (SVA) is a nonenveloped, single-stranded, positive-sense RNA virus in the family Picornaviridae. It was first discovered as a cell culture contaminant in 2002 but had been identified in US swine samples dating back to the late 1980s. Since swine were presumed to be…
Wild birds are the natural reservoirs of Influenza A viruses (IAVs) which cause occasional pandemics and seasonal epidemics. Avian IAVs can be transmitted from wild birds to domestic poultry, low mammals, and humans. It is well accepted that avian IAVs prefer to sialic acids (Si…