A doença no período pré-desmame tem um grande impacto no crescimento e na vida produtiva da futura vaca. Cerca de 50% das mortes que ocorrem no primeiro ano de vida acontecem nas primeiras 6 semanas. Este trabalho teve como objetivo avaliar a transferência de imunidade passiva (…
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Little is known about the role of the gastrointestinal microbiota in susceptibility to infection with enteric pathogens and response to live oral vaccines. This study examined the effect of immunization with an oral live-attenuated Shigella dysenteriae 1 vaccine and challenge wi…
The gut has a substantial resident microbiota localised in two major niches: the lumen and the intestinal mucus layer. The microbiota is vital for host health, yet the gut must also prevent uncontrolled incursion by pathogens or commensal microbes. Integral to host-microbe inter…
Introduction: Facemasks carrying a gelatine sampling matrix have been used to sample exhalations from TB patients. The aim here was to further develop this approach by evaluating molecular detection, quantitation and capture of signals in healthy volunteers and in HIV-uninfected…
Barrett's oesophagus (BO) arises from chronic gastro-oesophageal reflux disease(GORD). Patients have an increased risk of adenocarcinoma (ADC), which is the sixth most common cause of cancer mortality in the UK. All ADC develop from BO, and over the last twenty years there has b…
Background: Shigella spp . and enteroinvasive Escherichia coli (EIEC) are prominent enteric pathogens and estimates of prevalence are limited by suboptimal sensitivity of current detection methods. Recent studies have suggested common co-infection and frequent asymptomatic patho…