Production of soft red winter wheat ( Triticum aestivum ), the type of wheat used for baking cookies, crackers, and cakes, is known to be reduced by several biotic diseases; however, the impact of virus diseases on wheat health is widely underestimated in Ohio. This is partially…
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The interferon (IFN) system is a powerful antiviral defense system. Host cell pattern recognition receptors (PRRs) recognise pathogen-associated molecule patterns (PAMPs) which when activated, lead to the transcription of the IFN-β gene. As a consequence IFN is secreted from the…
The influenza A virus non-structural (NS1) protein is multifunctional, and during virus-infection NS1 interacts with several factors in order to manipulate host-cell processes. This study reports that NS1 binds directly to p85β, a regulatory subunit of phosphoinositide 3-kinase …
The henipaviruses, represented by Nipah virus (NiV) and Hendra virus (HeV), are emerging zoonotic paramyxoviruses responsible for repeated outbreaks in humans and animals associated with high morbidity and mortality in Australia, Southeast Asia, India and Bangladesh. Several spe…
In Indonesia, although the number of human fatalities from avian influenza is the largest globally, human influenza A is not a priority. There have been no studies on influenza A's burden, its risk factors, and its geographical distribution in the community. This information is …