Central massive objects like supermassive black holes and stellar nuclear clusters are common in all type of galaxies. I use N-body simulations to study the formation and evolution of nuclear clusters and to investigate the influence of the dynamical evolution of disc galaxies o…
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This thesis presents friction and wear rate measurements of the copper based bearing materials used in thrust bearing of aircraft fuel pumps. Highly detailed friction and wear data was collected from 20% and 30% lead in bronze (leaded bronze) substrates and 10% indium in lead (l…
Dendrimers are a novel class of highly branched polymers with a high degree of uniformity and monodispersity. As a result of the unique properties and characteristics of dendrimers, they have found a wide range of pharmaceutical applications. This study investigated the ability …
This research considers the ongoing challenge of semantics-based search from the perspective of how to exploit Semantic Web languages for search in the current Web environment. The purpose of the PhD was to use ontology-based query expansion (OQE) to improve search effectiveness…
The main focus of this research was to examine the molecular complexes formed by the proton sponge material DMAN [1,8-bis(dimethylamino)naphthalene]. It is well known that DMAN will readily protonate – forming the DMANH+ – leaving the second molecule in a DMAN complex negatively…
Service oriented Architecture (SoA) is a layered architecture for organising software resources as services, so that they can be deployed, discovered and combined to produce new Web services. One of the key challenges of SoA is in identifying the occurrence of failures that may …
The project objective was to advance the development of the H2 economy by improving biological H2 production in a sustainable way. Pseudo-continuous H2 production was achieved with improved efficiency, via the bacterial fermentation of sugars in a dual-bioreactor (‘upstream syst…
This study aimed to study the effect of potential large-scale bioreactor environmental heterogeneities during fed-batch culture on the performance of an industrially-relevant GS-CHO cell culture, producing an IgG antibody. Heterogeneity was created by a two-compartment scale-dow…
Mouse mammary gland morphogenesis at puberty is a complex developmental process, regulated by systemic hormones, local growth factors and dependent on the epithelial/epithelial and epithelial/stromal interactions. TEBs which invade the fat pad are important in laying down the ep…
The unique properties which make cerium dioxide (ceria) nanoparticles (NPs) so useful in e.g. catalytic applications, pose a real risk to environmental systems and species alike. Increasing our knowledge of ceria NP characteristics in a range of aquatic systems was a contributin…
Bulk samples of the lithium nitridometallates of the general form Li3-xMxN and Li3-x-yMxN, where M = Co, Ni and Cu, x ≤ 0.1 and y = vacancy, have been synthesised. The products of the syntheses have been characterised by Powder X-ray Diffraction (PND), Constant Wavelength Powder…
This PhD research project encompasses an investigation into the controlled behaviour of magnetic domain walls in patterned ferromagnetic nanostructures using advanced nanofabrication techniques and characterised by the techniques of transmission electron microscopy. By fabricati…
This mixed methods study investigates Palestinian science teachers' views of the nature of science (NOS), with an in-depth exploration of the nature, causes and context of these views, and the possible reasons why teachers hold such views. The research provides suggestions of po…
The GCSE science syllabus and curriculum changed considerably between 2005 and 2008. A key specification of coursework which had been identified as encouraging routine completion was replaced, requiring coursework to be completed under exam conditions, while a vocational alterna…
The challenge of abstract trademark image retrieval as a test of machine vision algorithms has attracted considerable research interest in the past decade. Current operational trademark retrieval systems involve manual annotation of the images (the current ‘gold standard’). Acco…
In recent years spatial light modulators (SLMs) have become an integral part of many optical trapping experiments. Yet their usefulness, which stems from their flexibility, is often under exploited. In this thesis I seek to demonstrate how it is possible to expand the range of o…
Chemokines are members of a family of small structurally related proteins, which can be classified according to the positioning of four conserved cysteine residues, into four families – CC, CXC, CX3C and XC. They have a wide range of functions, from being involved in embryonic d…
Survival, growth, aboveground biomass production, belowground biomass production, sediment accretion, soil surface elevation dynamics, sediment carbon and C/N ratio, sediment N and P, sediment 13C and 15N, sediment texture and macrofauna community structure, were studied in expe…
Mineral trioxide aggregate (MTA) is a Portland cement (PC)-based endodontic material used for sealing root canals. This study investigated the effect of calcium sulphate additions for improving the undesirably-long setting time of MTA-like dental materials, whilst maintaining th…